Epivir (Lamivudine)

Epivir
4.830 ratingsReviews
Generic:
Lamivudine
Indications:
HIV
Analogs:
Zeffix Emtriva Viread Vemlidy Baraclude Ziagen Truvada Descovy Dovato Triumeq Retrovir Combivir Epzicom Kivexa Hepsera
A well-known UK brand for lamivudine is Zeffix, while the name Epivir may be less familiar. The formulation is intended for similar use, and you can buy Epivir online today.
In stock: 16 packs
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Epivir 150 mg

Quantity Price per tablet You save Total price
30 £2.20 - £65.93
60 £1.73 £28.15 £103.71
90 £1.56 £57.04 £140.75
120 £1.41 £94.82 £168.90
180 £1.26 £168.16 £227.43
240 £1.14 £254.09 £273.36

Manufacturers

Cipla LimitedGlaxoSmithKlineMylanratiopharmSandozTeva CanadaTeva Pharmaceutical IndustriesViiV Healthcare

Payment & Delivery

Package Example

Your order is carefully packed and is dispatched within 24 hours. Here is what a typical package looks like.

Sized like a regular personal letter (approximately 24x11x0.7 cm), with no indication of what is inside.

Front View
Front View
Side View
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Back View
Back View
Delivery Times
Delivery MethodEstimated delivery
Express Free for orders over £222.24Estimated delivery to the UK: 4-7 days
Standard Free for orders over £148.16Estimated delivery to the UK: 14-21 days
EMSRoyal Mail
Payment Methods
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Discount Coupons

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Brand Names

Also known as (by country):
CountryBrand Names
United Kingdom
Zeffix

FAQ

Lamivudine tablets are prescription-only medicines when obtained from local UK pharmacies. Our store policy allows you to order this product without a prescription and have it sent by mail.

Do not increase the dose, extend treatment or stop lamivudine on your own. For HIV treatment, response is assessed with clinical review and viral-load testing rather than symptoms alone, so a lack of improvement or new symptoms should be assessed by the clinician managing the antiretroviral regimen.

Epivir 150 mg film-coated tablets are authorised in the United Kingdom, but we cannot confirm the regulatory status of the exact generic product supplied with an individual order. Check the received package label and manufacturer details for the specific product.

Do not take the tablets until the discrepancy has been checked. Compare the active ingredient, strength, dosage form, package label, lot number and expiry date with your order; this product is listed as lamivudine 150 mg tablets.

Keep the tablets in their package and check their condition and label before use. Lamivudine tablets should be stored at 25°C, with permitted excursions from 15°C to 30°C; because the actual temperature and duration of exposure may be unknown, do not use tablets that appear damaged or compromised until the issue is checked.

Tablets can normally travel by mail when kept in suitable protective packaging and handled in line with their labelled storage conditions. On arrival, check that the package is intact, dry and within date, and retain the tablets in their original packaging.

Epivir contains lamivudine, an antiretroviral medicine used with other antiretroviral medicines to treat HIV infection. Lamivudine also has activity against hepatitis B virus, but this 150 mg tablet product is presented for HIV treatment and should not be used as a stand-alone HIV treatment.

Take the tablets by mouth, with or without food, at the times prescribed as part of a combination HIV regimen. A common adult lamivudine regimen is 150 mg twice daily or 300 mg once daily, but the appropriate regimen may differ with kidney impairment and other treatment factors.

Commonly reported effects include headache, nausea, tiredness or malaise, diarrhoea, cough and nasal symptoms. Seek urgent medical help for symptoms suggesting a serious reaction, such as severe or persistent abdominal pain, repeated vomiting, unusual weakness, shortness of breath, yellowing of the skin or eyes, or a severe rash.

Lamivudine may be used during pregnancy when clinically needed, but the HIV regimen should be assessed and managed by a specialist. Breastfeeding should be avoided by people living with HIV, both because lamivudine passes into breast milk and because of the risk of HIV transmission.

Description

Note: Images in the description are provided for informational purposes and may differ from the actual appearance of the product. Please refer to the product name, strength, active ingredients, and pharmaceutical form.

Epivir 150 mg contains lamivudine (also known as "3TC"), a nucleoside reverse transcriptase inhibitor (NRTI) used with other antiretroviral medicines to treat HIV-1 infection.

Epivir (Lamivudine) 150 mg

How it works

Inside cells, lamivudine is converted into an active triphosphate form that inhibits HIV reverse transcriptase and blocks viral DNA synthesis. It helps reduce viral replication when taken as part of a full antiretroviral regimen, in line with standard HIV treatment practice in the UK.

Can Epivir (lamivudine) prevent HIV?

Epivir is mainly used to treat people living with HIV and is not used on its own for pre-exposure prophylaxis (PrEP). For prevention, clinical guidelines usually recommend dedicated PrEP options, such as tenofovir/emtricitabine or long-acting cabotegravir, depending on eligibility and local guidance.

For PrEP or post-exposure prophylaxis (PEP) options, speak to a clinician in the UK to find the most suitable choice.

Usual dosing (HIV-1)

  • Adults and adolescents: total daily dose 300 mg, taken as 150 mg twice daily or 300 mg once daily, as prescribed.
  • Can be taken with or without food.
  • Dose adjustment may be needed in renal impairment.

Abacavir plus lamivudine (ABC/3TC)

Abacavir + lamivudine (ABC/3TC) is a widely used backbone combination for HIV treatment. In some countries, it is available as a single fixed-dose tablet (for example, Epzicom or Kivexa) and is taken with at least one other antiretroviral medicine.

Epivir 150 mg tablets

Before starting abacavir-containing regimens, clinicians usually consider human leukocyte antigen B*5701 (HLA-B*5701) screening because of the risk of serious hypersensitivity reactions.

Important information

  • Epivir is taken with other antiretroviral medicines (not as monotherapy for HIV).
  • If you have HIV and hepatitis B virus (HBV), stopping lamivudine may cause a severe HBV flare-up. Do not stop treatment without medical advice.
  • Get urgent medical help if you have symptoms that could suggest lactic acidosis or severe liver problems.

This information is for general reference only and does not replace professional medical advice.

Medically reviewed by
Brian Holtry
MD, infectious diseases specialist and medical writer
Updated 6 August 2026

Customer questions

Asked by Hannah, Leeds, United Kingdom

I live in Leeds and want to make sure this medicine can be delivered to my postcode before I place an order. How can I check?

Answered by Support team

Enter your Leeds postcode at checkout to see whether delivery is available for your address before completing the order. Availability can vary, so checkout is the most reliable place to confirm it.

Asked by Rhys, Cardiff, United Kingdom

I have found what appears to be the same lamivudine generic elsewhere for almost half the price. Why should I order from you instead?

Answered by Support team

We stand behind the quality of the generic medicines we offer. We cannot verify what another seller supplies, how it is sourced or handled, or whether a similarly named cheaper product is genuinely equivalent in manufacturer, origin and quality. The choice is yours, but it is worth deciding whether the saving outweighs that uncertainty.

Asked by Aisha, Derby, United Kingdom

I work rotating shifts and realised after getting home that I missed my morning lamivudine dose. Should I take two tablets at my next usual time?

Answered by Support team
Medical reviewed by Brian Holtry

Do not take two doses together to make up for a missed dose. Take the missed dose when remembered unless it is nearly time for the next one; in that case, skip it and continue your usual schedule. If missed doses are becoming frequent, ask your HIV clinic or pharmacist for a dosing plan that fits your shifts.

Product specifications

Active ingredientLamivudine
Drug classNucleoside reverse transcriptase inhibitor (NRTI)
Dosage formTablets
Available strengths150 mg
RouteOral
StorageStore at 25°C; excursions permitted from 15°C to 30°C.
ATC codeJ05AF05

Regulatory information

United Kingdom: medicine status
Registration statusEpivir 150 mg film-coated tablets containing lamivudine are authorised in the United Kingdom under marketing authorisation PL 10592/0004.
Prescription statusLamivudine tablets are prescription-only medicines (POM) in the United Kingdom.
Marketing-authorisation holderThe marketing-authorisation holder for Epivir 150 mg film-coated tablets is ViiV Healthcare UK Ltd.
Safety monitoringSuspected side effects should be reported through the MHRA Yellow Card scheme.

More information