AntiInfectiveMeds
Since 2010
| Quantity | Price per tablet | You save | Total price | |
|---|---|---|---|---|
| 90 | £0.34 | - | £30.15 | |
| 120 | £0.31 | £2.94 | £37.26 | |
| 180 | £0.29 | £8.82 | £51.49 | |
| 270 | £0.26 | £19.71 | £70.75 | |
| 360 | £0.25 | £29.41 | £91.19 |
| Quantity | Price per tablet | You save | Total price | |
|---|---|---|---|---|
| 60 | £0.62 | - | £37.11 | |
| 90 | £0.54 | £7.45 | £48.23 | |
| 120 | £0.49 | £15.04 | £59.19 | |
| 180 | £0.45 | £30.52 | £80.82 | |
| 270 | £0.43 | £51.60 | £115.42 | |
| 360 | £0.41 | £75.41 | £147.27 |
Your order is carefully packed and is dispatched within 24 hours. Here is what a typical package looks like.
Sized like a regular personal letter (approximately 24x11x0.7 cm), with no indication of what is inside.
| Delivery Method | Estimated delivery |
|---|---|
| Express Free for orders over £222.24 | Estimated delivery to the UK: 4-7 days |
| Standard Free for orders over £148.16 | Estimated delivery to the UK: 14-21 days |
| Country | Brand Names |
|---|---|
| United Kingdom | Septrin |
Bactrim (sulfamethoxazole/trimethoprim) is a combination antibiotic containing sulfamethoxazole and trimethoprim. It is mainly used to treat a range of bacterial infections, including urinary tract infections, ear infections, bronchitis and pneumonia. The medicine works by blocking the production of folic acid in bacteria, which they need to grow and survive. It is effective against a wide range of bacterial pathogens. In the UK, its use depends on a clinician's assessment and local prescribing practice for the infection being treated.
Bactrim is a fixed-dose combination antibiotic that contains two active ingredients:
Combining these two antibiotics improves their effect against a broad range of bacterial pathogens. Together, they make Bactrim a versatile treatment option for different infections. The usual ratio in this formulation is one part trimethoprim to five parts sulfamethoxazole, which helps optimise their synergistic effects.
Bactrim is absorbed quickly after it is taken by mouth. Both sulfamethoxazole and trimethoprim are present in the blood in unbound, protein-bound and metabolised forms.
Peak blood levels of the individual components are reached 1 to 4 hours after oral administration. The mean serum half-lives of sulfamethoxazole and trimethoprim are 10 hours and 8 to 10 hours, respectively. However, in patients with severely impaired kidney function, the half-lives of both components increase, so the dosage regimen needs to be adjusted.
Sulfamethoxazole and trimethoprim are mainly excreted by the kidneys through both glomerular filtration and tubular secretion.
Bactrim is indicated for the treatment of many bacterial infections, including:
It may also help prevent infections such as toxoplasmosis and nocardiosis in certain high-risk groups.
Yes, Bactrim is a prescription-only medicine. Contact your healthcare provider. In the UK, they can assess whether treatment is needed based on the specific infection and your medical history. Self-medicating with antibiotics can lead to ineffective treatment and contribute to antibiotic resistance.
Bactrim is available in several forms, mainly oral tablets and liquid formulations. The most common tablet strengths include Bactrim 400 mg of sulfamethoxazole combined with 80 mg of trimethoprim. There is also a double-strength (DS) version, Bactrim DS, which contains 800 mg of sulfamethoxazole and 160 mg of trimethoprim.
Bactrim is also available in a liquid form for children. The dose is adjusted according to the child's weight. These formulations allow flexible dosing depending on the patient's needs and the type of infection being treated.
| Dosage Form | Strength | Brand Name | Composition/Features |
|---|---|---|---|
| Tablets | 400 mg sulfamethoxazole / 80 mg trimethoprim | Bactrim | Standard formulation |
| Tablets, DS (Double Strength) | 800 mg sulfamethoxazole / 160 mg trimethoprim | Bactrim DS | Double strength |
| Oral Suspension | 200 mg sulfamethoxazole / 40 mg trimethoprim per 5 mL | Bactrim Suspension | Sweetened for paediatric use |
| Intravenous (IV) Solution | 80 mg trimethoprim / 400 mg sulfamethoxazole per 5 mL | Bactrim IV | For hospital use |
To help reduce the development of drug-resistant bacteria and maintain the effectiveness of Bactrim (sulfamethoxazole and trimethoprim) tablets and other antibacterial medicines, the medicine should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. Using Bactrim (sulfamethoxazole and trimethoprim) tablets when there is no proven or strongly suspected bacterial infection, or no preventive indication, is unlikely to benefit the patient. It also increases the risk of drug-resistant bacteria developing.
Bactrim is typically taken twice daily, with or without food. The exact dose depends on the type of infection being treated:
| Condition | Patient Group | Dosage |
|---|---|---|
| Urinary Tract Infections | Adults | Bactrim DS (800 mg sulfamethoxazole/160 mg trimethoprim) one tablet every 12 hours for 10 to 14 days. |
| Children (2 months and older) | Dosage based on weight: approximately 40 mg/kg sulfamethoxazole and 8 mg/kg trimethoprim daily, divided into two doses. | |
| Acute Otitis Media | Children | Similar weight-based dosing as for urinary tract infections. |
| Bronchitis | Adults | One Bactrim DS tablet every 12 hours for 14 days. |
Taking Bactrim at evenly spaced intervals is important to maintain adequate levels of the medicine in the bloodstream.
If you miss a dose of Bactrim, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose - do not take a double dose. Taking it consistently helps maintain its effectiveness.
In the event of an overdose, seek immediate medical attention or contact a poisons service. Symptoms may include nausea, vomiting, dizziness or confusion. Prompt treatment is important to manage possible complications.
Several precautions should be taken when using Bactrim to help ensure safe and effective treatment. As dose adjustments may be needed, tell your healthcare provider about any pre-existing medical conditions, especially kidney or liver problems.
In addition, Bactrim is not recommended during pregnancy or while breastfeeding because of possible risks to the unborn baby or breastfed infant. Patients should also be aware of possible allergic reactions. Stop taking it and seek medical attention if severe skin reactions or other serious side effects occur.
Patients should be advised to drink enough fluids to help prevent crystalluria and kidney stone formation.
When Bactrim (sulfamethoxazole and trimethoprim) tablets are prescribed to treat a bacterial infection, patients should be told that although they may start to feel better early in treatment, the medicine should be taken exactly as directed.
Patients with a known allergy to sulfonamide antibiotics should avoid taking Bactrim because of the risk of severe allergic reactions, including Stevens-Johnson syndrome, anaphylaxis, toxic epidermal necrolysis, allergic myocarditis, exfoliative dermatitis, erythema multiforme, angioedema, drug fever, Henoch-Schönlein purpura, chills, serum sickness-like syndrome, widespread skin eruptions, generalised allergic reactions, photosensitivity, conjunctival and scleral injection, pruritus, urticaria and rash. Periarteritis nodosa and systemic lupus erythematosus have also been reported. It is important to tell healthcare providers about any previous allergic reactions before treatment.
People with certain health conditions should use Bactrim with caution:
This medicine is contraindicated in children younger than 2 months of age.
Although rare, deaths associated with the use of sulfonamides have occurred because of severe reactions, including Stevens-Johnson syndrome, fulminant hepatic necrosis, aplastic anaemia, toxic epidermal necrolysis, agranulocytosis and other blood dyscrasias.
Patients with AIDS may not tolerate or respond to Bactrim in the same way as patients without AIDS.
Regular monitoring may be needed during treatment in people with pre-existing conditions.
Common side effects associated with Bactrim include:
Serious side effects can occur, although they are rare. These include:
Clinical signs such as rash, sore throat, fever, arthralgia, pallor, purpura or jaundice may be signs of severe reactions.
Patients in the United Kingdom should report any unusual symptoms or side effects promptly to their healthcare provider.
Bactrim can interact with several medicines, which may increase the risk of side effects or reduce how well treatment works. These include:
Always tell your healthcare provider about all the medicines you are taking, including medicines bought without a prescription and supplements, to help avoid possible interactions.
After using Bactrim, it is important to store it properly. Any unused or expired tablets should also be disposed of safely.
Bactrim should be stored at room temperature, away from moisture and heat. Keep it out of the reach of children and pets. Proper storage helps maintain the medicine's effectiveness throughout its shelf life.
Do not flush unused or expired tablets down the toilet unless you have been told to do so. Ask your pharmacist about safe disposal methods or local guidance in the UK on disposing of medicines.
Bactrim (sulfamethoxazole/trimethoprim) is a combination antibiotic used to treat many bacterial infections. Understanding its composition, uses, precautions, dosing guidance, possible side effects and interactions with other medicines is important for safe and effective use. Always follow your healthcare provider's instructions and report any side effects or concerns during treatment.
I'm in Newry. Can I check whether Bactrim can be delivered to my address in Northern Ireland before I pay?
Yes. Enter your delivery address during checkout and use the delivery options shown there to check whether the product can be sent to your address. Availability should be confirmed by the checkout options rather than assumed for every area.
My order to Manchester has been dispatched. Does that mean it should arrive tomorrow?
Not necessarily. Dispatch means the order has been sent, while delivery is the later arrival event. Express delivery is estimated at 4-7 days and includes a tracking link by email after dispatch; standard delivery is typically 14-21 days without tracking.
Before ordering for Sheffield, can I use my postcode to see whether this medicine is available for delivery?
Yes. Add the product to your basket and enter your Sheffield postcode at checkout to view the delivery options available for that address. The checkout result is the appropriate confirmation of destination availability.
I share a house in Leicester and would prefer not to have medicine details printed on the parcel. Is the outer packaging discreet?
Yes. Orders are sent in discreet packaging, with no sensitive content or product details visible on the outside.
I take ramipril for high blood pressure. Is there anything important to check before I start these tablets?
Yes. Trimethoprim can increase potassium levels, and the risk is greater when it is taken with ramipril, particularly with kidney impairment or other potassium-raising medicines. A prescriber should review the combination and may arrange potassium and kidney-function monitoring.
| Active ingredient | Sulfamethoxazole and trimethoprim |
|---|---|
| Drug class | Sulfonamide antibiotic combination |
| Dosage form | Tablets |
| Available strengths | 400 mg/80 mg; 800 mg/160 mg |
| Route | Oral |
| Storage | Store at 20°C to 25°C, and protect from light. |
| ATC code | J01EE01 |
This product has 5 ratings, but only 3 written reviews so far. Share your experience and help other customers.
The tablets were a different colour from the pharmacy brand, as expected between brands; I checked the sulfamethoxazole and trimethoprim ingredients.
Bactrim order was spot on.
When I lived in London, delivery was usually two or three days quicker. This Bactrim order arrived without any problems.
