Doxycycline

Doxycycline
Generic:
Doxycycline
Indications:
acne amoeba infections malaria
Analogs:
Vibramycin Doryx Monodox Oracea Periostat Minocycline Tetracycline Lymecycline Azithromycin Erythromycin Amoxicillin Mefloquine Cefuroxime Clarithromycin Clindamycin Isotretinoin Levofloxacin
Doxycycline is an oral tetracycline antibiotic tablet, supplied by us in 100 mg and 200 mg strengths. Its active ingredient, doxycycline, is used worldwide to treat a broad range of bacterial infections, from chest and skin infections to acne, and to prevent malaria in travellers heading to endemic regions. Because tetracyclines can affect developing teeth and bone, Doxycycline isn't suitable for children under 12, pregnant women, or breastfeeding mothers. We let UK customers order Doxycycline tablets online without uploading a prescription, choosing from package sizes that match a short course or a longer acne or prophylaxis regimen.
In stock: 20 packs
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Doxycycline 100 mg

Quantity Price per tablet You save Total price
10 £2.58 - £25.84
20 £1.44 £22.93 £28.74
30 £0.86 £51.60 £25.91
60 £0.53 £123.46 £31.57
90 £0.41 £195.76 £36.78
120 £0.35 £267.54 £42.52
180 £0.28 £414.82 £50.26
270 £0.24 £631.87 £65.75
360 £0.22 £850.26 £79.90

Doxycycline 200 mg

Quantity Price per tablet You save Total price
30 £1.14 - £34.10
60 £0.74 £23.68 £44.53
90 £0.61 £47.28 £55.03
120 £0.54 £71.41 £65.00
180 £0.48 £118.62 £86.00
270 £0.44 £189.05 £117.87
360 £0.41 £259.87 £149.37

Manufacturers

AlphapharmApotex Inc.HexalJourney Medical CorporationLaboratoires BailleulMayne PharmaPfizerPfizer Italia S.r.l.Pierre Fabre Ibérica S.A.Teofarma

Payment & Delivery

Package Example

Your order is carefully packed and is dispatched within 24 hours. Here is what a typical package looks like.

Sized like a regular personal letter (approximately 24x11x0.7 cm), with no indication of what is inside.

Front View
Front View
Side View
Side View
Back View
Back View
Delivery Times
Delivery MethodEstimated delivery
Express Free for orders over £223.38Estimated delivery to the UK: 4-7 days
Standard Free for orders over £148.92Estimated delivery to the UK: 14-21 days
EMSRoyal Mail
Payment Methods
VisaMastercardAmerican ExpressJCBBitcoin, USDTApple PayGoogle PayPayPalKlarnaClearpay

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Brand Names

Also known as (by country):
CountryBrand Names
United Kingdom
Vibramycin-D

FAQ

Doxycycline is contraindicated during pregnancy and while breastfeeding in the United Kingdom. Tetracyclines can affect developing teeth and bones, and doxycycline passes into breast milk.

Description

Note: Images in the description are provided for informational purposes and may differ from the actual appearance of the product. Please refer to the product name, strength, active ingredients, and pharmaceutical form.

What Makes Doxycycline the Right Antibiotic Tablet for You?

Doxycycline tablets occupy an unusual middle ground among antibiotics: broad enough to cover respiratory, skin, and sexually transmitted infections, yet long-acting enough that most adults take them once or twice a day. We supply Doxycycline as 100 mg and 200 mg tablets, and the strength and pack size a reader chooses should match the specific reason doxycycline has been recommended, whether that's a short infection course, months of acne treatment, or a few weeks of travel protection against malaria. Understanding what sets this tetracycline apart from penicillins, macrolides, and newer alternatives helps make that choice with confidence rather than guesswork.

Doxycycline: Active Ingredient, Class, and Our Current Offer

Doxycycline belongs to the tetracycline class of antibiotics, a family discovered in the mid-twentieth century and still relied upon today for its unusually wide spectrum of activity. The tablets we list are oral and taken by mouth. Our 100 mg tablets are available in quantities of 10, 20, 30, 60, 90, 120, 180, 270, or 360, while our 200 mg tablets are available in quantities of 30, 60, 90, 120, 180, 270, or 360. We also stock Vibramycin, a differently branded presentation of the same active ingredient, for readers who prefer that naming or packaging.

Doxycycline's chemical structure allows it to penetrate tissues, including skin, lungs, and the prostate, more readily than many older tetracyclines, and its long half-life is what allows once-daily dosing in many regimens rather than the three or four daily doses older tetracyclines required.

Established Uses and When Doxycycline Is Typically Prescribed

Doctors turn to doxycycline for a genuinely broad set of problems, which is part of why it remains a mainstay antibiotic decades after its introduction. Recognised uses include:

  • Moderate to severe acne, where extended treatment can reduce inflammatory lesions.
  • Chest infections, including atypical pneumonia and exacerbations of chronic bronchitis.
  • Skin and soft tissue infections caused by susceptible bacteria.
  • Chlamydial infections and other specific sexually transmitted infections.
  • Lyme disease, where early treatment with doxycycline is a standard approach.
  • Prevention of malaria for travellers visiting regions where chloroquine resistance is common.
  • Certain amoebic infections, as an adjunct to other antiparasitic treatment.

Within the UK, malaria prophylaxis is a particularly common reason travellers ask about doxycycline, since it's one of the more affordable and widely tolerated options for trips to parts of Africa, Asia, and South America.

How Doxycycline Works and Why That Matters in Practice

Doxycycline is bacteriostatic rather than bactericidal: instead of rupturing bacterial cells outright, it binds to the 30S ribosomal subunit inside susceptible bacteria and blocks protein synthesis, which stops the bacteria multiplying and allows the immune system to clear the infection. This mechanism means doxycycline works only against susceptible organisms, so the infection and likely cause must guide whether it is an appropriate antibiotic. Its lipophilic nature lets it concentrate well in sebum and skin tissue, while additional anti-inflammatory effects help explain its established role in acne treatment over several weeks.

General Dosage, Administration, and Timing

Dosing varies considerably by indication, and the exact regimen should follow whatever a prescriber has specified, but some general patterns are well established. Many adult regimens use a 200 mg dose on the first day, sometimes split into two doses, followed by 100 mg once daily for the remainder of the course. Acne treatment often uses a lower daily dose over a longer period, while malaria prevention typically starts one to two days before travel, continues daily throughout the trip, and carries on for four weeks after returning, since it acts against malaria parasites after they enter the body rather than preventing the initial mosquito bite.

Doxycycline tablets should be swallowed with a full glass of water, and it helps to remain upright, or at least avoid lying down, for around thirty minutes afterwards, since the tablet can occasionally irritate the oesophagus if it lingers there. Doxycycline can generally be taken with food if it causes stomach upset, though the instructions supplied with the particular product should be followed.

Doxycycline and Timing: Practical Pointers

SituationPractical approach
Taking antacids or supplements containing iron, zinc, calcium, magnesium, aluminium, or bismuthSeparate these from doxycycline by at least two to three hours, as they can bind it and reduce absorption.
Sensitive stomachTake with a meal or snack, and milk if permitted by the product instructions, rather than on an empty stomach.
Sun exposureUse sunscreen and cover up, since doxycycline increases photosensitivity.
Malaria-prevention travelStart one to two days before departure and continue for four weeks after returning home.

Side Effects, Contraindications, and Interactions

Most people tolerate doxycycline well, but it's worth knowing what to watch for. Commonly reported effects include:

  • Nausea, stomach discomfort, or mild diarrhoea.
  • Photosensitivity, meaning sunburn occurs more easily.
  • Oesophageal irritation if the tablet isn't taken with enough water.
  • Occasional visual disturbance such as blurring, which matters for anyone driving or operating machinery.

Doxycycline is contraindicated in pregnancy and breastfeeding, because it crosses the placenta and passes into breast milk, where it can cause permanent tooth discolouration and affect bone growth in a developing baby or infant. It's also contraindicated in children under 12 for the same reason, and in anyone with a known hypersensitivity to doxycycline or other tetracyclines. Important interactions include:

  • Antacids and products containing aluminium, calcium, magnesium, iron, bismuth, or zinc, which can reduce absorption if taken too close together.
  • Warfarin and other anticoagulants, since doxycycline can enhance their effect.
  • Sulfonylurea medicines for diabetes, where doxycycline may increase the blood-glucose-lowering effect.
  • Retinoid acne treatments such as isotretinoin, which combined with tetracyclines carry a higher risk of raised pressure around the brain.

Special Populations, Continuity, and Storage

Older adults generally use the same adult dosing as younger adults. Dose adjustment is not usually required solely because of reduced kidney function, although significant liver impairment may require additional caution and monitoring. If a dose is missed, it's usually taken as soon as remembered unless the next dose is nearly due, in which case the missed dose is skipped rather than doubled up; maintaining the course without unplanned gaps matters most for infections and for malaria prevention, where missed doses can leave gaps in protection. We store Doxycycline tablets, and recommend customers store them, at 20°C to 25°C, with brief excursions between 15°C and 30°C tolerated, kept in a tightly closed container away from light and moisture.

Ordering Doxycycline in the UK: Access, Packing, and Delivery

Oral doxycycline tablets are classified as a prescription-only medicine under UK regulation, while doxycycline is authorised for human medicinal use in the UK. Separately, our own ordering policy doesn't require a prescription upload to accept an order, so UK customers can buy Doxycycline online from us in the listed 100 mg or 200 mg quantities. We've operated this catalogue since 2010, and every order is packed discreetly and dispatched for delivery across the UK. Our support team, including a pharmacist, is available 24/7 by email, online chat, or phone for questions about packaging, dispatch timing, or product information, and payment is processed in pounds sterling through our standard checkout. Readers comparing other antibacterial options may also find it useful to browse our wider antibiotics range alongside Doxycycline.

Doxycycline in Summary

Doxycycline remains one of the most versatile oral antibiotics available, covering everything from acne to malaria prevention through a single well-understood tetracycline mechanism. Getting the most from it comes down to matching the right strength and course length to the reason it's needed, respecting medicine and supplement timing so absorption isn't blunted, and being mindful of the small number of firm contraindications, particularly in pregnancy, breastfeeding, and young children. We make ordering straightforward for UK customers, with 100 mg and 200 mg Doxycycline tablets, flexible pack sizes, and round-the-clock support behind every delivery.

Medically reviewed by
Brian Holtry
MD, infectious diseases specialist and medical writer
Updated 10 November 2026

Product specifications

Active ingredientDoxycycline
Drug classTetracycline antibiotic
Dosage formTablet
Available strengths100 mg, 200 mg
Route of administrationOral
StorageStore at 20°C to 25°C; brief excursions permitted between 15°C and 30°C. Keep in a tightly closed container, protected from light and moisture.
ATC codeJ01AA02

Regulatory information

Marketing authorisationDoxycycline is fully approved and licensed for human medicinal use in the United Kingdom.
Dispensing categoryDoxycycline tablets are classified as a prescription-only medicine (POM) in the UK and require a valid prescription from an authorised healthcare professional.

More information