Secnidazole

Secnidazole
Indications:
bacterial vaginosis vaginal infection

Dosages

Secnidazole 1 g

Quantity Price per tablet Total price
20 £2.04 £40.74
30 £1.65 £49.63
60 £1.17 £70.38
120 £0.82 £98.53

Payment & Delivery

Package Example

Your order is carefully packed and is dispatched within 24 hours. Here is what a typical package looks like.

Sized like a regular personal letter (approximately 24x11x0.7 cm), with no indication of what is inside.

Front View
Front View
Side View
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Back View
Back View
Delivery Times
Delivery MethodEstimated delivery
Express Free for orders over £222.24Estimated delivery to the UK: 4-7 days
Standard Free for orders over £148.16Estimated delivery to the UK: 14-21 days
Payment Methods
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Brand Names

Also known as (by country):
CountryBrand Names
Bangladesh
Pronil DS Secnid Secnidal Secnizol Sezol DS
Belize
Secnidol Forte
Bosnia and Herzegovina
Sezol
Brazil
Deprozol Neodazol Secdazol Secfar Secnaxidol Secnidal Secnidazol Secnihexal Tecnid
Colombia
Daksol Secnidal Secnidazol Xemizol Zecnazol
Costa Rica
Secnidazol
Dominican Republic
Secnidazol
Ecuador
Amebial Amebizol Canvir Ecuzol Esnidazol Italnidazol Pazidol Xamex
Egypt
Amebazole Fladazole Flagentyl Opinidazole Senidal
El Salvador
Secnidazol
France
Secnol
Georgia
Biazox Secdaza Secnidox Secnil Tagera Forte
Guatemala
Secdazol Secnidazol Secnidol Forte
Honduras
Secnidazol
India
Ambiform Etisec Secnil Forte
Lebanon
Flagentyl Secnol
Mexico
Gisistin Minovag Secnidal
Nicaragua
Secnidazol
Pakistan
A-sec Dysen Forte Enirobe Ganidal Ganidal Forte Liviat Nidaz
Panama
Secnidazol
Peru
Bianos Secnidazol Seczol Triconella
Portugal
Flagentyl
Tanzania
Fladazole
Turkey
Flagentyl Secnidox
United States
Solosec
Venezuela
Ambese Daksol Fazol Secnidazol Secnivax Seczol Unidazol
Vietnam
Dazoserc Flagentyl Secnol

Description

Note: Images in the description are provided for informational purposes and may differ from the actual appearance of the product. Please refer to the product name, strength, active ingredients, and pharmaceutical form.

This medicine is used to treat certain protozoal infections and infections caused by susceptible anaerobic bacteria. Its active ingredient is secnidazole, a 5-nitroimidazole antimicrobial. It may work against organisms such as Trichomonas vaginalis, Giardia lamblia, and Entamoeba histolytica, as well as some anaerobic bacteria (depending on local susceptibility patterns and product information).

Secnidazole Mechanism of Action

Secnidazole and other 5-nitroimidazoles enter susceptible microorganisms and undergo enzymatic reduction of the nitro group in anaerobic organisms and certain protozoa. Reactive metabolites can damage DNA and inhibit growth.

Secnidazole 1 g

How to Take the Medication?

Secnidazole 1 g is supplied as a film-coated tablet in some markets. Take it by mouth with water exactly as prescribed. Do not take more than the dose prescribed or use it for longer than your healthcare professional recommends.

For adults, some product information uses 2 g as a single dose (that is, two 1 g tablets or four 500 mg tablets) for conditions such as intestinal amoebiasis, giardiasis and trichomoniasis. Some product information also includes bacterial vaginosis. Dosing can vary depending on the infection and the country. In the UK, hepatic amoebiasis regimens may require treatment over several days - follow local product information and your clinician's instructions.

Uses

Secnidazole is an antimicrobial medicine. Using it when it is not needed may contribute to resistance. Use it only when it has been prescribed for an infection that is proven or strongly suspected.

Secnidazole vs Albendazole vs Metronidazole vs Tinidazole

Medicine Drug class What it is typically used for Common regimen (adult, examples) Key cautions / notes Alcohol advice
Secnidazole Nitroimidazole (antimicrobial / antiprotozoal) Bacterial vaginosis and trichomoniasis in some markets, depending on local product information and availability. Often used as a single-dose treatment by mouth in markets where the medicine is available, for example 2 g once. Do not use in people with hypersensitivity to secnidazole or other nitroimidazoles. If trichomoniasis is being treated, sexual partners should also be assessed and treated where appropriate to help reduce the risk of reinfection. Avoid alcohol during treatment and follow the product information for any advice after the dose.
Metronidazole Nitroimidazole (antibacterial / antiprotozoal) Anaerobic bacterial infections, protozoal infections, and commonly bacterial vaginosis and trichomoniasis. Usually given as a course over several days, depending on the indication and formulation. For example, oral metronidazole is commonly used for bacterial vaginosis in UK practice. Avoid unnecessary use. Do not use with disulfiram taken within the previous 2 weeks. Metronidazole may interact with warfarin and other coumarin anticoagulants. Do not drink alcohol during treatment and for at least 48 hours afterwards.
Tinidazole Nitroimidazole (antiprotozoal / anaerobic antibacterial) Trichomoniasis, giardiasis and amoebiasis where available. Often given as a single-dose treatment for some protozoal infections, with courses over several days for others, depending on the indication and local product information. May interact with warfarin and other oral anticoagulants. Avoid use with disulfiram. Availability varies, and tablets may not be routinely available in the UK. Avoid alcohol during treatment and for 3 days after the last dose.
Albendazole Anthelmintic (benzimidazole) Helminth infections (worm infections), not bacterial vaginosis or trichomoniasis. Usually given as a short course or a longer regimen, depending on the infection, body weight and specialist advice. Liver function and blood counts may need to be monitored with longer courses. Avoid use in pregnancy unless clearly necessary. Use depends on the indication and local availability. No specific disulfiram-like alcohol warning is usually highlighted.

Note: Your product is secnidazole 1 g. Availability, dosing and licensed indications may vary depending on the formulation and local product information. Always follow the product information and the advice of your doctor or pharmacist.

Contraindications and Precautions

Do not use secnidazole if you have hypersensitivity to secnidazole or other imidazole (nitroimidazole) derivatives. Some product information advises avoiding use during the first trimester of pregnancy and while breastfeeding; in the UK, follow the local product information and your clinician's advice.

Avoid alcohol during treatment and for at least 24 hours after the last dose. Do not use it together with disulfiram.

Drug Interactions

Tell your healthcare professional about all the medicines you take. Secnidazole may increase the effect of warfarin and other oral anticoagulants, so monitoring may be needed.

Possible Side Effects

Side effects are usually mild and temporary. Reported side effects with nitroimidazoles can include gastrointestinal upset (nausea, abdominal pain), headache, dizziness and a metallic taste. Seek urgent medical attention if you have signs of a severe allergic reaction, such as swelling of the face or throat, or trouble breathing.

Storage

Store below 30°C (86°F). Protect from light and moisture. Keep out of the sight and reach of children.

Reviewed by
Brian Holtry
MD, infectious diseases specialist and medical writer

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