Zyvox (Linezolid)

Zyvox
3.813 ratingsReviews
Generic:
Linezolid
Indications:
infections
Analogs:
Vancomycin Daptomycin Tedizolid Ceftaroline Tigecycline Dalbavancin Oritavancin Clindamycin Linezolid Sivextro Cubicin Teflaro Dalvance Orbactiv Tygacil Bactrim Synercid
In stock: 14 packs
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Zyvox 600 mg

Quantity Price per tablet You save Total price
30 £4.49 - £134.83
60 £4.26 £14.08 £255.58

Manufacturers

Accord HealthcareCipla LimitedLaboratorios NormonPfizerPfizer CanadaratiopharmSandoz

Payment & Delivery

Package Example

Your order is carefully packed and is dispatched within 24 hours. Here is what a typical package looks like.

Sized like a regular personal letter (approximately 24x11x0.7 cm), with no indication of what is inside.

Front View
Front View
Side View
Side View
Back View
Back View
Delivery Times
Delivery MethodEstimated delivery
Express Free for orders over £222.24Estimated delivery to the UK: 4-7 days
Standard Free for orders over £148.16Estimated delivery to the UK: 14-21 days
EMSRoyal Mail
Payment Methods
VisaMastercardAmerican ExpressJCBBitcoin, USDTApple PayGoogle PayPayPalKlarnaClearpay

Discount Coupons

  • New Year's Day - 1 January 2026 9% NEWYEAR9
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  • Boxing Day - 26 December 2026 10% BOXING10
  • New Year's Eve - 31 December 2026 8% NYE8

Brand Names

Also known as (by country):
CountryBrand Names
United Kingdom
Linezolid Accord

FAQ

Linezolid is a prescription-only medicine and a prescription is required when buying it from local UK pharmacies. Our store policy allows you to order it without a prescription and have it sent by mail.

Take linezolid for the full duration prescribed, even if symptoms improve sooner, unless the prescriber tells you to stop. Stopping early can leave the infection insufficiently treated and may contribute to bacterial resistance.

Take the missed dose when you remember, unless it is nearly time for the next dose. In that case, skip the missed dose and continue with the usual schedule; do not take two doses together or an extra dose.

Yes. The active ingredient is linezolid, the same medicine ingredient associated with the Zyvox name. The available product is an oral 600 mg film-coated tablet; packaging, manufacturer, tablet appearance and inactive ingredients can vary.

A different appearance alone does not mean a tablet is incorrect. Compare the active ingredient, 600 mg strength, film-coated tablet form, manufacturer, package label, lot number, expiry date and any imprint present. Do not take the tablets until the discrepancy is checked if the ingredient, strength, dosage form, seal or physical condition appears wrong or compromised.

Store the tablets at 25°C; temperature excursions between 15°C and 30°C are permitted. Protect them from light and moisture, and keep bottles tightly closed. Keep the medicine in its labelled packaging and out of the sight and reach of children.

Linezolid is an oxazolidinone antibiotic used for certain serious infections caused by susceptible Gram-positive bacteria. Established uses include hospital-acquired and community-acquired pneumonia, skin and soft-tissue infections, and some infections caused by vancomycin-resistant Enterococcus faecium. It does not treat viral illnesses and is not generally used for Gram-negative infections.

Linezolid should be avoided during pregnancy unless it is clearly necessary, because human pregnancy data are limited and animal studies found reproductive toxicity. Breastfeeding should be avoided before and throughout treatment, as linezolid and its metabolites may pass into breast milk.

Common side effects include nausea, diarrhoea, headache, altered taste and vomiting. More serious effects can include low blood cell counts, unusual bruising or bleeding, severe or persistent diarrhoea, visual changes, numbness or tingling, and lactic acidosis. Urgent medical advice is needed for signs of a serious allergic reaction, severe rash, confusion, fever with muscle stiffness, or other possible serotonin syndrome symptoms.

Linezolid 600 mg film-coated tablets may be taken with or without food. Avoid foods and drinks high in tyramine, such as mature cheeses, cured or pickled foods, yeast extracts and some alcoholic drinks, because linezolid can increase the risk of a dangerous rise in blood pressure with large tyramine amounts.

Description

Note: Images in the description are provided for informational purposes and may differ from the actual appearance of the product. Please refer to the product name, strength, active ingredients, and pharmaceutical form.

Zyvox (linezolid) is an oxazolidinone antibiotic used to treat certain serious infections caused by susceptible Gram-positive bacteria. In UK clinical practice, it may be prescribed for appropriate infections when a clinician considers linezolid suitable.

Drug class

Linezolid belongs to the oxazolidinone class of antibiotics.

How it works

Linezolid blocks bacterial protein synthesis at an early stage by preventing formation of the 70S initiation complex.

What Zyvox tablets treat (and what they do not)

Illness / condition (A-Z) Zyvox tablets
Community-acquired pneumonia (CAP) +
Complicated skin and soft tissue infections +
Diabetic foot infection (without concomitant osteomyelitis) +
Gonorrhoea -
Gram-negative infections (e.g., E. coli, Pseudomonas) -
Hospital-acquired / nosocomial pneumonia (HAP) +
Osteomyelitis -
Pressure ulcers -
Uncomplicated skin and soft tissue infections +
Urinary tract infection (UTI) -
VRE (Enterococcus faecium) infection, including cases with concurrent bacteraemia +
Viral infections (flu/common cold) -
Yeast or other fungal infections -

Limitations of use (UK): Zyvox is not indicated for treating Gram-negative infections. If a Gram-negative pathogen is suspected or confirmed, appropriate treatment should be started.

Indications (US labelling)

Zyvox tablets are used for certain infections caused by susceptible Gram-positive bacteria, including pneumonia (nosocomial and community-acquired), skin and soft tissue infections (complicated and uncomplicated), and vancomycin-resistant Enterococcus faecium (VRE) infections, including cases with concurrent bacteraemia.

Tablet strength

Tablet: 600 mg (film-coated).

Can you split the tablet?

Zyvox 600 mg tablets are film-coated and are not supplied as scored tablets in the UK. For this reason, splitting or crushing them is generally not recommended unless a clinician specifically advises it.

Zyvox

Why is Zyvox expensive? Are there alternatives?

Cost can be influenced by brand pricing, manufacturing and supply chain factors, and market conditions. Depending on the infection and culture/susceptibility results, clinicians may choose alternatives. Generic linezolid tablets are available in the UK and may cost less than the branded product in some settings.

What medicines is it used with?

Zyvox may be used on its own for confirmed susceptible Gram-positive infections. If an infection is mixed or a Gram-negative pathogen is suspected, clinicians may prescribe Zyvox together with other antibiotics that cover Gram-negative organisms and, when needed, anaerobes. The exact combination depends on the site of infection, its severity, and local resistance patterns.

Drug interactions

Linezolid is a reversible, non-selective MAO inhibitor (MAOI). It can interact with adrenergic drugs, which may raise blood pressure, and serotonergic drugs, which may increase the risk of serotonin syndrome. Tell your UK clinician about all prescription medicines, medicines you buy without a prescription, and herbal products you use.

Contraindications

Contraindication What it means
Hypersensitivity to linezolid (or any component of the product) Do not use if you have a known serious allergy to linezolid or any of the ingredients in the product.
Use with MAO inhibitors (or within 2 weeks of stopping an MAOI) Do not use with MAOIs (e.g., phenelzine, isocarboxazid, selegiline) or within 2 weeks of stopping them because of the risk of interactions.

Tyramine (food interaction)

Because linezolid has MAOI activity, avoid consuming large amounts of tyramine-rich foods and drinks during treatment. Examples include mature cheeses, cured, aged or improperly stored meats, fermented foods (including some soya and yeast products), and certain alcoholic drinks such as some beers and red wine. Seek medical help if you develop a severe headache, flushing, or a marked rise in blood pressure.

Side effects and key precautions

Common side effects include diarrhoea, nausea, vomiting, and headache.

Important warnings and precautions include myelosuppression (including thrombocytopenia; full blood counts are commonly monitored weekly), peripheral and optic neuropathy (reported mainly with treatment lasting longer than 28 days), lactic acidosis, seizures, and C. difficile-associated diarrhoea. Report unusual bruising or bleeding, severe or persistent diarrhoea, or new visual symptoms promptly, including blurred vision or changes in visual acuity or colour vision.

Storage

Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F).

Medically reviewed by
Donna Brettler
BPharm, MPH - Pharmacologist and medical writer
Updated 6 August 2026

Customer questions

Asked by Customer, London, United Kingdom

I'm Priya in London and want to make sure I can read the instructions before ordering. Will the leaflet in the pack be in English?

Answered by Support team

We cannot confirm the leaflet language in advance because it may vary by the package supplied. Check the received carton and leaflet before use, and make sure the label confirms linezolid 600 mg film-coated tablets.

Asked by Customer, Edinburgh, United Kingdom

I have chronic kidney disease and have dialysis three times a week. Does linezolid need a lower dose for me?

Answered by Support team
Medical reviewed by Brian Holtry

Linezolid usually does not require a routine dose reduction solely for kidney impairment, but its inactive metabolites can build up when kidney function is severely reduced. For someone receiving dialysis, the timing and monitoring of treatment need to be confirmed by the clinician managing the infection.

Product specifications

Active ingredientLinezolid
Drug classOxazolidinone antibiotic
Dosage formFilm-coated tablet
Available strengths600 mg
RouteOral
StorageStore at 25°C; excursions permitted to 15°C to 30°C. Protect from light and keep bottles tightly closed to protect from moisture.
ATC codeJ01XX08

Regulatory information

United Kingdom: medicine status
Registration statusZyvox 600 mg film-coated tablets (linezolid) are a UK authorised prescription medicine.
Prescription statusLinezolid is prescription-only medicine (POM) in the United Kingdom.
Marketing authorisation holderFor the UK Zyvox tablet authorisation, the marketing authorisation holder is Pfizer Limited.
NHS access and chargesNHS supply is subject to a prescriber's clinical decision and local antimicrobial policies; prescription charges may apply in England unless the patient is exempt, while NHS prescriptions are generally free in Scotland, Wales and Northern Ireland.
Safety monitoringSuspected side effects should be reported through the MHRA Yellow Card Scheme; linezolid requires particular attention to blood-count changes, neuropathy and interactions with serotonergic medicines.

More information