Nizoral (Ketoconazole)

Nizoral
4.129 ratingsReviews
Generic:
Ketoconazole
Indications:
fungus
Analogs:
Clotrimazole Miconazole Terbinafine Ciclopirox Selenium Sulfide Fluconazole Itraconazole Ketoconazole Canesten Lotrimin Daktarin Lamisil Econazole Loprox Diflucan Sporanox
In stock: 15 packs
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Nizoral 200 mg

Quantity Price per tablet You save Total price
30 £1.95 - £58.52
60 £1.49 £27.41 £89.64
90 £1.32 £57.04 £118.53
120 £1.25 £83.71 £150.38
180 £1.17 £140.01 £211.13
270 £1.12 £224.46 £302.25
360 £1.10 £305.21 £397.07

Manufacturers

Cipla Limited

Payment & Delivery

Package Example

Your order is carefully packed and is dispatched within 24 hours. Here is what a typical package looks like.

Sized like a regular personal letter (approximately 24x11x0.7 cm), with no indication of what is inside.

Front View
Front View
Side View
Side View
Back View
Back View
Delivery Times
Delivery MethodEstimated delivery
Express Free for orders over £222.24Estimated delivery to the UK: 4-7 days
Standard Free for orders over £148.16Estimated delivery to the UK: 14-21 days
EMSRoyal Mail
Payment Methods
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FAQ

A prescription is required to obtain ketoconazole 200 mg tablets from local pharmacies in the United Kingdom. Our store policy allows you to place an order without a prescription and have it sent by mail. This ordering policy does not change the medicine's prescription-only status in the UK.

Store the tablets at 20°C to 25°C; short excursions between 15°C and 30°C are permitted. If they were exposed to more extreme temperatures, or for an unknown or prolonged period, keep them in their packaging and check the label and tablet condition before use. Do not use tablets that are wet, crumbling, discoloured or otherwise visibly altered.

Not necessarily. Tablets supplied under a different name or by a different manufacturer can differ in colour, shape, size, markings and packaging. The important identifiers are ketoconazole as the active ingredient, the 200 mg strength and the tablet dosage form.

Do not take the product if it is not tablets, as ordered. Check the active ingredient, strength, dosage form, manufacturer details, lot number and expiry date against the package label, then have the discrepancy checked before using it. A cream, shampoo or another form of ketoconazole is not interchangeable with oral 200 mg tablets.

Alcohol should be avoided while taking oral ketoconazole. Both alcohol and ketoconazole can affect the liver, and combining them may increase the risk of liver injury. Seek urgent medical advice for yellowing of the skin or eyes, dark urine, persistent nausea, unusual fatigue or upper abdominal pain.

Ketoconazole is an azole antifungal, but oral ketoconazole is no longer authorised in the UK for routine treatment of fungal infections because of the risk of serious liver injury. Oral 200 mg ketoconazole tablets have specialist use in managing endogenous Cushing's syndrome. They are not a routine treatment for dandruff, scalp conditions or ordinary skin fungal infections.

Ketoconazole tablets should be avoided during pregnancy because of potential risks to the developing baby, including findings from animal studies and the medicine's effects on steroid production. They should also be avoided during breastfeeding because ketoconazole passes into breast milk. Anyone who becomes pregnant or wishes to breastfeed while taking the tablets needs prompt specialist advice about treatment.

These are oral tablets, swallowed with water exactly as directed for the condition being treated. Taking ketoconazole with food may reduce stomach irritation, but medicines that reduce stomach acid can lower ketoconazole absorption and require a clinical review. The dose and monitoring plan must be selected by the prescriber because oral ketoconazole has important liver, adrenal and drug-interaction risks.

Description

Note: Images in the description are provided for informational purposes and may differ from the actual appearance of the product. Please refer to the product name, strength, active ingredients, and pharmaceutical form.

Uses

Ketoconazole tablets (oral ketoconazole) are used to treat certain serious fungal infections in the body only when other effective antifungal treatment is not available or cannot be tolerated and when the potential benefits are judged to outweigh the risks.

Ketoconazole tablets are used for systemic fungal infections only when other antifungal treatments have failed or cannot be tolerated, including blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis (chromoblastomycosis), and paracoccidioidomycosis.

This medicine should not be used as initial treatment for severe, life-threatening infections. Because levels in the cerebrospinal fluid (CSF) after oral use are unpredictable, ketoconazole tablets should not be used to treat fungal infections of the central nervous system (CNS), including fungal meningitis. Close follow-up during and after treatment is recommended.

Blastomycosis

Oral ketoconazole is used to treat blastomycosis caused by Blastomyces dermatitidis in selected patients when other effective antifungal treatment is not available or cannot be tolerated. Severe disease, including suspected CNS involvement, generally needs specialist care and alternative systemic treatment.

Ketoconazole for blastomycosis

Chromomycosis

Oral ketoconazole has been used for chromomycosis (chromoblastomycosis) caused by Phialophora spp. Response can vary, and treatment should be tailored by a clinician experienced in systemic fungal infections.

Coccidioidomycosis

Oral ketoconazole is used for mild to moderate coccidioidomycosis in selected patients when other effective treatments cannot be used. Severe lung disease or widespread infection needs intensive antifungal treatment under medical supervision.

Histoplasmosis

Oral ketoconazole is used for histoplasmosis caused by Histoplasma capsulatum in selected patients when other effective treatments are not available or cannot be tolerated. The choice of treatment depends on how severe the illness is, immune status, and clinical response.

Paracoccidioidomycosis

Oral ketoconazole is used to treat paracoccidioidomycosis (South American blastomycosis) caused by Paracoccidioides spp., particularly when alternative antifungal treatment is not available or cannot be tolerated.

Ketoconazole for paracoccidioidomycosis

Dosage and Directions

Take ketoconazole tablets exactly as prescribed by your doctor.

The usual starting dose for adults is 200 mg once daily. In severe infections, or if the expected clinical response is not achieved, the dose may be increased to 400 mg once daily, depending on clinical response and tolerability.

Use in children: ketoconazole tablets have not been systematically studied in children. Use in paediatric patients is generally avoided unless a specialist decides that the potential benefit outweighs the risks.

Administration

Ketoconazole needs stomach acid to be absorbed properly. Medicines that reduce stomach acid, such as antacids, H2-blockers, and proton pump inhibitors, may reduce absorption. If you take acid-reducing medicines or have low stomach acid, ask your prescriber or pharmacist how to take ketoconazole and how to space your doses.

Important Safety Information

Ketoconazole tablets can cause serious side effects, including severe liver injury (which may be fatal or require a liver transplant), adrenal insufficiency, and QT prolongation (serious heart rhythm problems). Your healthcare provider may order blood tests to check your liver function before and during treatment.

When to seek medical help

Stop taking ketoconazole tablets and get medical help straight away if you develop symptoms of liver injury, such as loss of appetite, nausea/vomiting, unusual tiredness, stomach pain, dark urine, pale stools, yellowing of the skin or eyes, fever, or rash.

Precautions

Tell your healthcare provider if you have liver problems now or have had them in the past, heart rhythm problems, adrenal problems, or if you take multiple medicines, including products you buy without a prescription and supplements. Avoid alcohol while taking ketoconazole tablets.

Contraindications

Ketoconazole tablets are contraindicated in patients with known hypersensitivity to ketoconazole.

Because ketoconazole can prolong the QT interval and cause serious drug interactions, taking it with certain medicines is contraindicated. Examples listed in official product information include dofetilide, quinidine, pimozide, cisapride, methadone, disopyramide, dronedarone, and ranolazine (and in some labelling, lurasidone), due to the risk of life-threatening ventricular dysrhythmias such as torsades de pointes.

Taking ketoconazole with certain benzodiazepines, such as oral midazolam or triazolam, is contraindicated because ketoconazole can greatly increase their levels and effects.

Pregnancy and Breastfeeding

Pregnancy: Tell your healthcare provider if you are pregnant or planning to become pregnant. It is not known whether ketoconazole tablets will harm your unborn baby.

Breastfeeding: Ketoconazole can pass into breast milk. You and your healthcare provider should decide whether you will take ketoconazole tablets or breastfeed. You should not do both.

Possible Side Effects

Side effects may include nausea, abdominal discomfort, diarrhoea, headache, dizziness, and abnormal liver function test results. Ketoconazole can interfere with steroid biosynthesis and may cause endocrine-related side effects (e.g., gynecomastia, menstrual irregularities, decreased libido, or adrenal suppression), especially at higher doses.

Drug Interactions

Ketoconazole is a strong inhibitor of CYP3A4 and has many clinically significant drug interactions. Some combinations are contraindicated because of the risk of serious heart rhythm problems (QT prolongation), excessive sedation, or other severe side effects.

Drug classes that may interact include medicines that affect heart rhythm, certain sedatives, some cholesterol-lowering medicines, immunosuppressants, anticoagulants, and many others. Tell your healthcare provider and pharmacist about all prescription medicines, medicines you buy without a prescription, vitamins, and herbal supplements you take before starting ketoconazole.

Medicines that affect stomach acid (antacids, H2-blockers, PPIs, sucralfate) may reduce ketoconazole absorption. Ask a pharmacist about spacing doses if these medicines are needed.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue with your usual schedule. Do not take two doses at the same time.

Overdose

In the event of an overdose, seek urgent medical advice. In the UK, call 111 for advice if the person is not seriously unwell, or call 999 / go to A&E in an emergency. Treatment is supportive.

Storage

Ketoconazole tablets should be protected from moisture and stored in well-closed containers at 15-25°C (59-77°F). Keep out of the reach of children.

Medically reviewed by
Donna Brettler
BPharm, MPH - Pharmacologist and medical writer
Updated 6 August 2026

Customer questions

Asked by James, Portsmouth, United Kingdom

I have used ketoconazole shampoo before, but need to know what form you sell. Are these tablets or a topical product?

Answered by Support team

This catalogue listing is for oral ketoconazole tablets at a strength of 200 mg. It is not a shampoo, cream or other topical ketoconazole product.

Asked by Sarah, Coventry, United Kingdom

My daughter is 11 and has been referred for possible Cushing's syndrome. Can these 200 mg ketoconazole tablets be used in children?

Answered by Support team
Medical reviewed by Donna Brettler

For oral ketoconazole, use is established from age 12 for endogenous Cushing's syndrome; safety and effectiveness below age 12 have not been established. An 11-year-old's treatment needs a paediatric specialist to decide on an appropriate option and monitoring plan.

Product specifications

Active ingredientKetoconazole
Drug classAzole antifungal
Dosage formTablet
Available strengths200 mg
RouteOral
StorageStore at 20°C to 25°C; excursions permitted between 15°C and 30°C. Protect from moisture and light.
ATC codeJ02AB02

Regulatory information

United Kingdom: ketoconazole tablet status
Registration statusOral ketoconazole 200 mg tablets, including Nizoral tablets, are no longer authorised for routine marketing in the United Kingdom because of the risk of serious liver injury.
Prescription statusKetoconazole 200 mg oral tablets were prescription-only medicines when authorised in the UK.
Safety monitoringSuspected adverse reactions to ketoconazole should be reported to the MHRA through the Yellow Card scheme, particularly signs of liver injury.

More information