Flagyl ER (Metronidazole)
Dosages
Flagyl ER 200 mg
| Quantity | Price per tablet | Total price | |
|---|---|---|---|
| 120 | £0.27 | £32.60 | |
| 180 | £0.23 | £41.48 | |
| 270 | £0.21 | £55.56 | |
| 360 | £0.19 | £68.89 |
Flagyl ER 400 mg
| Quantity | Price per tablet | Total price | |
|---|---|---|---|
| 90 | £0.40 | £36.30 | |
| 120 | £0.36 | £43.71 | |
| 180 | £0.33 | £58.52 | |
| 270 | £0.30 | £81.49 | |
| 360 | £0.29 | £102.97 |
Payment & Delivery
Your order is carefully packed and is dispatched within 24 hours. Here is what a typical package looks like.
Sized like a regular personal letter (approximately 24x11x0.7 cm), with no indication of what is inside.
| Delivery Method | Estimated delivery |
|---|---|
| Express Free for orders over £222.24 | Estimated delivery to the UK: 4-7 days |
| Standard Free for orders over £148.16 | Estimated delivery to the UK: 14-21 days |
Discount Coupons
- New Year's Day - 1 January 2026 9% NEWYEAR9
- Valentine's Day - 14 February 2026 6% VALENTINE6
- St David's Day - 1 March 2026 4% DAVID4
- St Patrick's Day - 17 March 2026 5% PATRICK5
- St George's Day - 23 April 2026 4% GEORGE4
- May Day - 1 May 2026 5% MAYDAY5
- Halloween - 31 October 2026 6% HALLOWEEN6
- Guy Fawkes Night - 5 November 2026 5% GUY5
- Christmas Eve - 24 December 2026 9% XMASEVE9
- Christmas Day - 25 December 2026 10% XMAS10
- Boxing Day - 26 December 2026 10% BOXING10
- New Year's Eve - 31 December 2026 8% NYE8
Brand Names
| Country | Brand Names |
|---|---|
 Argentina | Bexon Colpofilin Dazotron Epaq Etronil Flagyl Format Ginkan Gynotran Metral Metrocev Metrodermic Metrolocal Nalox Noritate Ovufem Padet Repligen Rozex Taremis Tolbin Tricofin Trimstat |
 Australia | Flagyl Metrogyl Metronide Metrozine Protostat Rozex Trichozole Zidoval |
 Belgium | Anaeromet Flagyl Pharmaflex Rosaced Rozex |
 Brazil | Ambrosil Amebil Astergyl Canderm Candifen Dalzolston Flagyl Flanizol Ginovagin Helmizol Metrizol Metrodax Metrogyl Metronib Metronide Metroniflex Metronil Metronin Metronix Metrotix Metroval Metrozol Minegyl Neo Metrodazol Odonid Rozex |
 Canada | Flagyl Florazole Metrocream Metrogel Metrolotion Neo-Metric NidaGel Noritate Novo-Nidazol Trikacide |
 Czechia | Deflamon Efloran Entizol Klion Medazol Rosalox Rozex |
 Denmark | Elyzol Flagyl Metrogel Rozex Zidoval |
 Finland | Elyzol Flagyl Rosazol Rozex Trikozol Zidoval |
 France | Collazole Elyzol Flagyl Grinazole Imizine Metrocol Metrogene Rosiced Rozacreme Rozagel Rozex |
 Germany | Arilin Clont Elyzol Flagyl Fossyol Infectoclont Metrocreme Metrogel Metrolotion Metronid-Puren Metronimerck Metronour Metront Metrosa Rathimed Rathimed N Rosiced Tricho Cordes Ulcolind Metro Vagi-Metro Vagimid |
 Greece | Acsacea Colpocin-T Dermaskin Elyzol Emedal Flagolin Flagyl Gnostol Metrazol Metrogyl Pedryl Periotret Robaz Rosiced Trichovagil Tricodazole Unitrim |
 Hungary | Klion Rozex Supplin |
 Italy | Deflamon Elyzol Flagyl Gineflavir Pernyzol Rosased Rosiced Rozex Vagilen Zidoval |
 Malaysia | Flagyl Fogyl Frotin Metronol Protogyl Ranigyl Rozex Setrozole |
 Mexico | Ameblin Amiyodazol Antral Biomona Biotazol Cryozol Dasmetrol Dasolin Dualizol Elyzol Epaq Fagizol Fartricon Flagenase Flagenol Flagepat Flaginazol Flagyl Flamin Flaxtec Fresenizol Fusanidazol Hemestal Juaflor Labitrix Lagylan Lamblit Lozad Medazol Medizol Meredazol Messeldazol Metosan Metricom Metrizol Metrobendizol Metrocream Metrogel Metronil Metroson Mibazol Milezzol Niacel Nidazolem Nidralon-V Nidrozol Nitromidager Ortrizol Otrozol Ovazol-V Planizol Proflag Promibasol Prozolin Retofar Samonil Selegil Servizol Solumidazol Stomffler Valpar Vanestrin-V Vatrix-S Vertisal |
 Netherlands | Anaeromet Elyzol Flagyl Metrogel Nidazea Rosiced Rozex |
 New Zealand | Flagyl Rozex Trichozole |
 Norway | Elyzol Flagyl Rozex Zidoval |
 Poland | Metrosept Rozex |
 Portugal | Dumozol Elyzol Flagyl Metroderme Norstene Rodermil Roseless Rosiced |
 Spain | Amotein Flagyl Rozex Tricowas B Zidoval |
 Sweden | Elyzol Flagyl Rozex Zidoval |
 Turkey | Flagyl Metrajil Metrazol Metrosel Nidazol Roza |
 United States | Flagyl Metizol Metric Metro Metrocream Metrogel Metrogel Vaginal Noritate Protostat Vandazole |
Description
This medicine is called Flagyl (metronidazole). It belongs to a group of medicines known as antibiotics/antiprotozoals. In the UK, it is prescribed by a clinician to treat certain bacterial and protozoal infections.
What is Metronidazole?
It can be used to:
- treat serious infections caused by susceptible anaerobic bacteria (for example, intra-abdominal infections, skin and skin structure infections, gynaecological infections, bacteraemia/septicaemia, central nervous system infections, lower respiratory tract infections, and endocarditis);
- treat trichomoniasis and amoebiasis (FDA-approved uses for FLAGYL tablets).
Clinicians in the UK may also prescribe it for other uses, depending on local guidelines and individual factors (off-label use).
Metronidazole is also available as a vaginal gel (0.75%) to treat bacterial vaginosis. This is a different formulation/product from oral Flagyl tablets. Vaginal gel labelling includes once-daily dosing for 5 days for bacterial vaginosis.
Pharmacokinetics
After oral administration, metronidazole is well absorbed, with peak plasma concentrations reached 1 to 2 hours later. The average elimination half-life in healthy people is about 8 hours. Approximately 20% of the dose is excreted unchanged in the urine. Metronidazole appears in cerebrospinal fluid and other tissues at concentrations similar to those in plasma.
How to Take Metronidazole
Always take this medicine exactly as your doctor has told you. It is important to complete the full course of treatment. How long you need to take it for will depend on your condition and the infection being treated.
Check with your doctor or pharmacist if you are not sure.
- Swallow the tablets whole with a drink of water
- Do not crush or chew the tablets
- Take them exactly as prescribed
Typical adult oral regimens in UK prescribing information (examples; your prescriber may individualise dosing):
| Indication | Patient group | Dosage | Frequency / duration |
|---|---|---|---|
| Trichomoniasis | Adults | 2 g total | Either as a single dose or as 1 g twice on the same day; or 250 mg |
| Trichomoniasis | Adults | 250 mg | Three times daily for 7 days |
| Amoebiasis (acute intestinal) | Adults | 750 mg | Three times daily for 5 to 10 days |
| Amoebic liver abscess | Adults | 500 mg or 750 mg | Three times daily for 5 to 10 days |
| Anaerobic bacterial infections | Adults | 7.5 mg/kg (about 500 mg for a 70-kg adult) | Every 6 hours; max 4 g/day (duration often 7 to 10 days) |
Paediatric use: safety and effectiveness in children have not been established, except for the treatment of amoebiasis (paediatric dosing is based on body weight and should be prescribed by a clinician).
Your doctor will decide how much to take and how often, depending on the type and severity of the infection.
People Having Kidney Dialysis
Haemodialysis can remove a substantial amount of metronidazole from the bloodstream. If dosing cannot be separated from the dialysis session, your prescriber may consider an extra dose after haemodialysis depending on your clinical situation.
People with Liver Problems
Your doctor may tell you to use a lower dose or take the medicine less often. A dose reduction is recommended in severe hepatic impairment.
If You Take More Metronidazole Than You Should
If you take more than you should, contact your doctor or go to the nearest A&E department immediately. If possible, take the box, this leaflet, and any tablets left over with you so the doctor knows what you have taken.
If You Forget to Take the Dose
If you miss a dose, take it as soon as you remember and then continue as usual. If it is nearly time for your next dose, skip the missed dose and carry on as usual. Do not take a double dose to make up for a forgotten dose.
If you have any further questions about using this product, ask your doctor or pharmacist.
Important Safety Information
Do not take Metronidazole Tablets if you are allergic (hypersensitive) to metronidazole or other nitroimidazole derivatives. Signs of an allergic reaction include a rash, problems swallowing or breathing, and swelling of your lips, face, throat, or tongue.
Alcohol warning: Do not drink alcohol (and avoid products containing propylene glycol) while you are taking metronidazole and for at least 3 days after finishing your course. Drinking alcohol while taking metronidazole may cause unpleasant side effects such as nausea, vomiting, stomach pain, flushing, headache, and cramping.
Pregnancy and Breastfeeding
Tell your doctor before taking this medicine if you are pregnant, might become pregnant, or think you may be pregnant.
- Trichomoniasis: metronidazole tablets are contraindicated during the first trimester. If treatment is needed later in pregnancy and alternative treatment has been inadequate, the one-day (2 g) regimen should generally be avoided because it results in higher serum levels.
- Other indications: published studies include first-trimester exposure; discuss the risks and benefits with your clinician.
- Breastfeeding: metronidazole passes into breast milk. Because of the potential for tumorigenicity seen in animal studies, a decision should be made whether to stop breastfeeding or stop the drug. Alternatively, a breastfeeding mother may express and discard milk during treatment and for 24 hours after treatment ends, and feed stored human milk or formula.
Ask your doctor or pharmacist for advice before taking any medicine.
Driving and Using Machines
While taking metronidazole, you may feel sleepy, dizzy, or confused, see or hear things that are not there (hallucinations), have fits (convulsions), or have temporary eyesight problems such as blurred or double vision. If this happens, do not drive or use machinery or tools.
Your doctor may want to carry out some tests if you have been taking this medicine for more than 10 days.
Possible Side Effects
Metronidazole is generally well tolerated. Common side effects can include nausea, a metallic taste, and stomach upset. Serious nervous system effects (including seizures, encephalopathy, optic or peripheral neuropathy) have been reported, particularly with prolonged use; stop taking the medicine and seek medical advice if you develop symptoms such as numbness, tingling, weakness, vision changes, or severe dizziness.
Stop taking metronidazole and see a doctor or go to hospital straight away if you get swelling of the hands, feet, ankles, face, lips, or throat, which may cause difficulty swallowing or breathing. You may also notice an itchy, raised rash (hives) or nettle rash (urticaria). This may mean you are having an allergic reaction.
Speak to your doctor straight away if you notice yellowing of the skin or eyes (jaundice), unusual bruising or bleeding, severe tiredness (possible blood effects), or severe stomach pain that may spread through to your back (pancreatitis).
Long-Term Use
Metronidazole has shown tumorigenicity in mice and rats; unnecessary use should be avoided and treatment should be reserved for appropriate indications.
Interactions
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines. This includes medicines bought without a prescription, including herbal medicines.
- Disulfiram: do not use metronidazole if you have taken disulfiram within the last 2 weeks.
- Alcohol / propylene glycol: avoid during treatment and for at least 3 days after the last dose.
- Warfarin and other coumarin anticoagulants: metronidazole may increase the risk of bleeding; monitoring or dose adjustment may be needed.
- Lithium (may increase lithium toxicity; monitoring may be needed).
- Busulfan (may increase busulfan exposure/toxicity).
- Phenytoin, phenobarbital (may alter metronidazole levels and effects).
- Ciclosporin / tacrolimus (levels may increase; monitoring may be needed).
Storage and Stability: Store below 25°C and protect from light.
